September 23, 2022
Apolipoprotein A1, B and Ratio 载脂蛋白A1,B和比率

It has been suggested that Apo B is a more reliable indicator of Cardiovascular disease (CVD) than LDL-C, since measurement of Apo B is a direct quantitation rather than a calculated measurement. Apo Bassay is also not affected by hypertriglyceridemia as is the case with the calculated LDL-C. While LDL-C continues to constitute the primary target of therapy, the Canadian Cardiovascular Society (CCS) 2009 guideline has identified Apo B as an alternate primary target of hyperlipidemia therapy.


Apo A1 is the protein component of HDL-C and its concentration is inversely related to risk of CVD. The CCS 2009 guideline includes target values for the ratio of Apo B/Apo A.

Use of Test: Assessment of Cardiovascular Disease Risk.